Bridge Dialysis
Acute kidney injury (AKI) is a common complication of severe trauma, affecting 19-40% of trauma patients and causing increased rates of morbidity and mortality even in patients who survive their initial life-threatening injuries. It is critical for these patients to have rapid access to dialysis equipment, but battlefield hospitals and far-forward deployed surgical teams may be unable to access the large volumes of dialysate fluid required. In order to avoid the high logistical cost of shipping aqueous solutions into battlefield locations and to ensure continual access to this potentially lifesaving treatment, it would be preferable to produce dialysate on demand in the field using locally available water sources.
TDA Research, Inc. (TDA) has developed a lightweight, portable device to produce dialysate fluid on demand in austere locations using no electrical power. The generator will use forward osmosis (FO) and a series of purification steps to produce sterile dialysate fluid from potable and non-potable water sources. Not only will this technology dramatically reduce logistical costs associated with shipping dialysate fluid, it will ensure that supply chains are not interrupted and field hospitals are never without access to dialysate when patients develop AKI while waiting for evacuation.
Compact, single-person portable, ruggedized, battery-operated, advanced filtration system for serum potassium to serve as a bridge dialysis system in the post traumatic care of combat casualties suffering from hyperkalemia.
Operates for a minimum of 6 hours to fill the gap before an appropriate renal replacement therapy (RRT) can be provided.
Uses an advanced low silica X (LSX) zeolite that will remove only the K+ ions via a highly selective ion exchange process.
TDA’s bridge dialysis system will control the potassium levels in hyperkalemia patients in the expeditionary environment and improve their survival rate.
